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Edward Hellriegel Selected Research

Bendamustine Hydrochloride

5/2021Bendamustine treatment of Chinese patients with relapsed indolent non-Hodgkin lymphoma: a multicenter, open-label, single-arm, phase 3 study.
6/2015Pharmacokinetic and pharmacodynamic profile of bendamustine and its metabolites.
11/2014Population pharmacokinetics and pharmacokinetics/pharmacodynamics of bendamustine in pediatric patients with relapsed/refractory acute leukemia.
6/2014An evaluation of the potential for drug-drug interactions between bendamustine and rituximab in indolent non-Hodgkin lymphoma and mantle cell lymphoma.
3/2013Pharmacokinetics and excretion of 14C-bendamustine in patients with relapsed or refractory malignancy.
7/2012Metabolite profiling of bendamustine in urine of cancer patients after administration of [14C]bendamustine.

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Edward Hellriegel Research Topics

Disease

4Non-Hodgkin Lymphoma (Lymphosarcoma)
05/2021 - 06/2014
4Neoplasms (Cancer)
11/2014 - 07/2012
3Hematologic Neoplasms (Hematological Malignancy)
06/2015 - 03/2013
2Infections
06/2015 - 11/2014
1Tardive Dyskinesia
01/2021
1Chorea (Rheumatic Chorea)
01/2021
1Huntington Disease (Huntington's Disease)
01/2021
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
10/2016
1Fatigue
10/2016
1Sleep Initiation and Maintenance Disorders (Insomnia)
10/2016
1Anemia
10/2016
1Headache (Headaches)
10/2016
1Migraine Disorders (Migraine)
09/2016
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
06/2015
1Nausea
06/2015
1Leukemia
11/2014
1Body Weight (Weight, Body)
11/2014
1Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
06/2014

Drug/Important Bio-Agent (IBA)

6Bendamustine HydrochlorideFDA Link
05/2021 - 07/2012
2Rituximab (Mabthera)FDA Link
06/2015 - 06/2014
2Alkylating AgentsIBA
06/2015 - 03/2013
1deutetrabenazineIBA
01/2021
1Tetrabenazine (Nitoman)FDA Link
01/2021
16- (4- (3- (2- methylpyrrolidin- 1- yl)propoxy)phenyl)- 2H- pyridazin- 3- oneIBA
10/2016
1Tyrosine Kinase InhibitorsIBA
10/2016
1HomoharringtonineIBA
10/2016
1tyramine-deoxysorbitolIBA
09/2016
1Sumatriptan (Imigran)FDA LinkGeneric
09/2016
1Cytochrome P-450 CYP1A2 (CYP1A2)IBA
11/2014